Jennifer A. Barrie

This study shows that peripheral inflammation triggers fat pad atrophy and lymph node expansion via macrophage activity, supporting immune response energy needs.

This study shows that CCR1/2/3/5 deletion reduces CD4 T cell responses but not CD8 T cell responses to influenza virus infection.

This study investigates neuroinflammation in mice driven by TLR7 activation, finding global immune activation and region-specific neuronal gene expression changes in mood-related brain areas.

This study identifies thalamostriatal circuit disruption as a conserved neuroinflammatory mechanism linking systemic inflammation to depression and anhedonia in humans and mice.