A CyclinB2-Cas9 fusion promotes the homology-directed repair of double-strand breaks
Manuel M. Vicente, Afonso Mendes, M. Jason de la Cruz, José R. Vicente, Vasco M. Barreto
This paper describes a CyclinB2-Cas9 fusion protein that enhances homology-directed repair of double-strand breaks by promoting Cas9 activity during the G2 phase of the cell cycle.
bioRxiv · Feb 20, 2019 · PreprintMolecular Biology