Molecular BiologybioRxivPreprint
Single-cell landscape reveals NAMPT mediated macrophage polarization that regulate smooth muscle cell phenotypic switch in pulmonary arterial hypertension
Zuoshi Wen, Liujun Jiang, Fangcong Yu…·Ting Chen
The paper uses scRNA-seq to analyze pulmonary arteries in PAH and healthy donors, identifying NAMPT-mediated macrophage polarization that drives SMC phenotypic switching.