Overlapping MHC class I/II Epitopes Program cDC1-like Differentiation of Monocyte-Derived Dendritic Cells via mTORC1 Signaling Inhibition
Sharon Bright Amanya, Arnav Murthy, Nalini Bisht…·WK Decker
The paper shows that overlapping MHC class I/II epitopes promote cDC1-like differentiation of moDC through mTORC1 inhibition, enhancing type 1 immunity.