Author

Nicola Losito

National Research CouncilORCID 0000-0002-2991-4848Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alice ChiodiiD· 1 shared Arianna ConsiglioiD· 1 shared Azhar AliiD· 1 shared Chiara CavalliniiD· 1 shared Elena LevantiniiD· 1 shared Emilia BramantiiD· 1 shared Ettore MoscaiD· 1 shared Eva Cabrera San MillániD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alice ChiodiORCID

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1 paper

Recent·Most cited

The two sides of resistance: aggressiveness and mitotic instability as the Achilles heel of Osimertinib-resistant NSCLC

Paolo Armanetti, Eva Cabrera San Millán, Raffaella Mercatelli, Chiara Cavallini, Alice Chiodi, Ettore Mosca, Arianna Consiglio, Nicola Losito, Luca Menichetti, Emilia Bramanti, Azhar Ali, Elena Levantini, Giorgia Maroni

This study identifies BMI1 as a driver of Osimertinib resistance in NSCLC by promoting mitotic instability and aggressiveness, and shows that targeting BMI1 with Unesbulin can suppress tumor growth.

bioRxiv · Sep 25, 2025 · PreprintCancer Biology