The mechanisms of siRNA selection by plant Argonaute proteins triggering DNA methylation
Wei Liu, Keisuke Shoji, Masahiro Naganuma, Yukihide Tomari, Hiro‐oki Iwakawa
This study investigates how AGO4 and AGO6 in Arabidopsis load 24A siRNAs, revealing distinct mechanisms and identifying the MID-PIWI domain coordination as key to 5' A specificity.
Nucleic Acids Research · Dec 7, 2022Peer-reviewedMolecular Biology