Yukihide Tomari

The paper develops a scalable assay and a protein language model to predict monomeric yield of proteins in E. coli, showing it can be learned and designed.

The paper identifies ribosome stalling as a mechanism that enhances chloroplast targeting of nuclear-encoded proteins in Arabidopsis thaliana.

The paper compares piRNA sequence repertoires in two silkworm cell lines and finds that repertoire changeability negatively correlates with piRNA biogenesis efficiency due to competition between adjacent ping-pong sites.

This study identifies Spn-E's dual role in facilitating heterotypic ping-pong piRNA amplification while suppressing homotypic ping-pong in silkworms.

The paper identifies a naive piRNA surveillance system that broadly monitors the germline transcriptome for newly invading elements, showing it is abundance-coupled and independent of canonical piRNA pathways.

This paper introduces a new method to efficiently induce human spinal lower motor neurons from iPSCs and presents a single-cell evaluation system using time-lapse microscopy and machine learning.

The paper identifies torimochi as an active, expanding retrotransposon in silkworm cells that produces piRNAs and may function as a dynamic piRNA cluster.

This study investigates how AGO4 and AGO6 in Arabidopsis load 24A siRNAs, revealing distinct mechanisms and identifying the MID-PIWI domain coordination as key to 5' A specificity.

This study shows that GW182 is essential for miRNA-mediated gene silencing in Drosophila, affecting larval development despite some survival and repression capabilities.

This study identifies Hero proteins as heat-resistant proteins that stabilize other proteins and prevent aggregation, extending lifespan in Drosophila.