Author

Carmenza Spadafora

Instituto de Investigaciones Científicas y Servicios de Alta TecnologíaORCID 0000-0002-3002-9467Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Eduardo Antônio Ferraz CoelhoiD· 1 shared Haruna Luz Barazorda-CcahuanaiD· 1 shared José L. Medina‐FrancoiD· 1 shared Laura Pineda R· 1 shared Luis Daniel Goyzueta-MamaniiD· 1 shared Michelle G. NgiD· 1 shared Miguel Á. Chávez‐FumagalliiD· 1 shared Mónica Florin‐ChristenseniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBioinformatics

Eduardo Antônio Ferraz CoelhoORCID

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Author profile →

1 paper

Recent·Most cited

From Proteome Mining to Structural Validation: Phosphopyruvate Hydratase as a Structurally Tractable Drug Target in Kinetoplastid Parasites

Luis Daniel Goyzueta-Mamani, Haruna Luz Barazorda-Ccahuana, Michelle G. Ng, Laura Pineda R, José L. Medina‐Franco, Mónica Florin‐Christensen, Eduardo Antônio Ferraz Coelho, Carmenza Spadafora, Miguel Á. Chávez‐Fumagalli

The paper identifies phosphopyruvate hydratase (PPH) as a drug target in kinetoplastid parasites through proteome mining, structural modeling, and experimental validation, and identifies hinokinin as a promising antiparasitic compound.

bioRxiv · Jun 12, 2026 · PreprintBioinformatics