Author

Mónica Florin‐Christensen

Consejo Nacional de Investigaciones Científicas y TécnicasORCID 0000-0003-0456-3970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1 Approach:simulation· 1

Frequent Co-Authors

Eduardo Antônio Ferraz CoelhoiD· 2 shared Haruna Luz Barazorda-CcahuanaiD· 2 shared José L. Medina‐FrancoiD· 2 shared Luis Daniel Goyzueta-MamaniiD· 2 shared Miguel Á. Chávez‐FumagalliiD· 2 shared Alexsandro Sobreira GaldinoiD· 1 shared Carmenza SpadaforaiD· 1 shared Laura Pineda R· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Eduardo Antônio Ferraz CoelhoORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 12, 2026

From Proteome Mining to Structural Validation: Phosphopyruvate Hydratase as a Structurally Tractable Drug Target in Kinetoplastid Parasites

Luis Daniel Goyzueta-Mamani, Haruna Luz Barazorda-Ccahuana, Michelle G. Ng…·Miguel Á. Chávez‐Fumagalli

The paper identifies phosphopyruvate hydratase (PPH) as a drug target in kinetoplastid parasites through proteome mining, structural modeling, and experimental validation, and identifies hinokinin as a promising antiparasitic compound.

DOI 10.64898/2026.06.09.731156

humanmouse

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BioinformaticsbioRxivPreprintMar 14, 2024

Targeting Leishmania infantum Mannosyl-oligosaccharide glucosidase with natural products: pH-dependent inhibition explored through computer-aided drug design.

Luis Daniel Goyzueta-Mamani, Haruna Luz Barazorda-Ccahuana, Mayron Antonio Candia-Puma…·Miguel Á. Chávez‐Fumagalli

The paper evaluates natural products for anti-leishmanial activity against Leishmania infantum MOGS using CADD, identifying Ocotillone and Subsessiline as promising candidates with pH-dependent inhibition and favorable ADMET profiles.

DOI 10.1101/2024.03.14.585122

statistical modeldrug response / drug discovery

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