Author

Anastassia N. Alexandrova

University of California, Los AngelesORCID 0000-0002-3003-1911Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1

Frequent Co-Authors

Alfredo Arrigo SaduniD· 1 shared Daniel GuioniD· 1 shared Pujan AjmeraiD· 1 shared Steven BarnesiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

Alfredo Arrigo SadunORCID

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1 paper

Recent·Most cited

Molecular Basis of Mitochondrial Complex I Disruption by m.14484T>C-Induced Leber Hereditary Optic Neuropathy

Pujan Ajmera, Daniel Guion, Steven Barnes, Alfredo Arrigo Sadun, Anastassia N. Alexandrova

This study identifies how the m.14484T>C mutation in ND6 subunit of complex I disrupts quinone binding and proton pumping, leading to LHON through altered hydrogen bond networks and redox chemistry.

bioRxiv · Apr 23, 2026 · PreprintBiophysics