Author

Sergey A. Kozin

Engelhardt Institute of Molecular BiologyORCID 0000-0002-3018-7932Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A.A Makarov· 1 shared Aleksei V TrukhiniD· 1 shared Anastasia A. AnashkinaiD· 1 shared Arthur Tigranovich KopyloviD· 1 shared Dmitriy M. ChudakoviD· 1 shared E.A Kolobova· 1 shared Ekaterina M. MerzlyakiD· 1 shared Ekaterina V. BarsovaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A.A Makarov

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2 papers

Recent·Most cited

BCR repertoire analysis and cloning of antibody candidates targeting native and Asp7-isomerized β-amyloid

Н. А. Николаев, M.Yu. Myshkin, E.A Kolobova, Irina A. Shagina, O.I. Kechko, K. B. Varshavskaya, Ekaterina V. Barsova, T.V. Grigoreva, V.A. Mitkevich, Ekaterina M. Merzlyak, Sergey A. Kozin, A.A Makarov, Dmitriy M. Chudakov, Sergey Lukyanov, Irina Grigorova, Olga V. Britanova

The paper demonstrates a repertoire-guided workflow to prioritize antibody candidates targeting β-amyloid and its isoAsp7 proteoform, identifying potential heavy-light chain combinations through computational and experimental methods.

bioRxiv · Oct 13, 2026 · PreprintImmunology

Beyond Alzheimer's story: how an engineered molecule gained an endogenous essence

Arthur Tigranovich Kopylov, Ruslan Yu. Yakovlev, Aleksei V Trukhin, Yuri M. Poluektov, Anastasia A. Anashkina, Sergey A. Kozin

The paper identifies HAEE as an endogenous blood plasma component reduced in Alzheimer's patients, suggesting it as a biomarker and potential therapeutic agent.

bioRxiv · Sep 22, 2025 · PreprintNeuroscience