Sibylle Pfammatter

This study identifies PKL complexes in plants that recognize H3K4me3 and regulate gene expression at promoters through chromatin remodeling.

The paper generates a benchmark dataset to evaluate proteomics instruments and workflows using high-throughput LC gradients across multiple platforms and organisms.

This study uses AI-based image analysis and multi-omics profiling to link morphological features with molecular changes in ccRCC, identifying unique molecular profiles in aggressive rhabdoid tumors.

SPAT annotates proteins based on their likelihood to be at the cell surface using existing annotations, showing good performance on leukemia and public datasets.