Author

Alyssa C. Lesko

University of Virginia Health SystemORCID 0000-0002-3031-7610Unclaimed ORCID profile · follow to get notified of new preprints

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Developmental Biology· 1

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Approach:experimental assay· 1 Organism:mouse· 1

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Ann E. SutherlandiD· 1 shared Ping CheniD· 1 shared Ray E. KelleriD· 1 shared

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2021-2021 · peak 1/yr

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Ann E. SutherlandORCID

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Developmental BiologyDevelopmental BiologyPeer-reviewedMay 21, 2021

Scribble mutation disrupts convergent extension and apical constriction during mammalian neural tube closure

Alyssa C. Lesko, Ray E. Keller, Ping Chen, Ann E. Sutherland

This study shows that Scribble mutations disrupt neural tube closure by impairing cell intercalation, apical constriction, and junctional protein expression in mouse embryos.

24 citations

mouseexperimental assay

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