Author

Ann E. Sutherland

University of Virginia Health SystemORCID 0000-0003-1925-2825Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Assay:imaging· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Alyssa C. LeskoiD· 1 shared Arielle HoganiD· 1 shared Deepthi S. Vijayraghavan· 1 shared Esha Fateh· 1 shared Jasmine WangiD· 1 shared Lance A. DavidsoniD· 1 shared Margaret C. M. SmithiD· 1 shared Matthew Smith· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperDevelopmental Biology

Alyssa C. LeskoORCID

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3 papers

Recent·Most cited

Inferring active and passive mechanical drivers of epithelial convergent extension

Sommer Anjum, Deepthi S. Vijayraghavan, Rodrigo Fernández‐González, Ann E. Sutherland, Lance A. Davidson

This study uses simulations and live cell imaging to distinguish active and passive mechanical drivers of convergent extension in developing tissues.

bioRxiv · Jan 28, 2025 · PreprintBiophysics

Rac1 and Nectin3 are essential for PCP-directed axon guidance in the peripheral auditory system

Shaylyn Clancy, Nicholas Xie, Tess Eluvathingal Muttikkal, Jasmine Wang, Esha Fateh, Margaret C. M. Smith, Phillip Wilson, Matthew Smith, Arielle Hogan, Ann E. Sutherland, Xiaowei Lu

This study identifies Rac1 and Nectin3 as novel regulators of PCP-directed axon guidance in type II spiral ganglion neurons during auditory system development.

bioRxiv · Jun 5, 2024 · PreprintDevelopmental Biology

Scribble mutation disrupts convergent extension and apical constriction during mammalian neural tube closure

Alyssa C. Lesko, Ray E. Keller, Ping Chen, Ann E. Sutherland

This study shows that Scribble mutations disrupt neural tube closure by impairing cell intercalation, apical constriction, and junctional protein expression in mouse embryos.

Developmental Biology · May 21, 2021Peer-reviewedDevelopmental Biology