Rana S. Aldisi

Multimodal evidence for impaired glymphatic brain clearance as a mediator of "inflammaging" in schizophrenia - integrating insights from in vivo neuroimaging, omics, and post-mortem single nucleus-RNA-Seq data

The paper integrates neuroimaging, omics, and single nucleus-RNA-Seq data to show glymphatic dysfunction in schizophrenia is linked to inflammation, aging, and cognitive decline.

Trans-ancestry polygenic models for the prediction of LDL blood levels: An analysis of the UK Biobank and Taiwan Biobank

This paper compares ancestry-specific and multi-ancestry polygenic risk scores for LDL prediction in East Asian populations using UK Biobank and Taiwan Biobank data, finding that multi-ancestry models are more generalizable.

Breast and prostate cancer risk: the interplay of polygenic risk, high-impact monogenic variants, and family history

This study assesses how polygenic risk scores, high-impact monogenic variants, and family history influence breast and prostate cancer risk using UK Biobank data.

Assessing the role of polygenic background on the penetrance of monogenic forms in Parkinson's disease.

This study examines how polygenic risk scores influence the penetrance of monogenic Parkinson's disease variants and family history in Parkinson's disease risk.

Re-curation and Rational Enrichment of Knowledge Graphs in Biological Expression Language

The paper develops workflows to re-curate and enrich knowledge graphs encoded in Biological Expression Language using automated and manual methods.