Generation of a bloodstream form Trypanosoma brucei double glycosyltransferase null mutant competent in receptor-mediated endocytosis of transferrin
Samuel M. Duncan, Carla G. Carbajo, Rupa Nagar, Qi Zhong, Conor J. Breen, Michael A. J. Ferguson, Calvin Tiengwe
This paper creates double null mutants of TbGT8 and TbGT10 in Trypanosoma brucei, showing reduced pNAL synthesis but normal TfR function and parasite viability.
PLoS Pathogens · Jun 27, 2024Peer-reviewedMolecular Biology