Author

Richard Mariadasse

Alagappa UniversityORCID 0000-0002-3041-6993Unclaimed ORCID profile · follow to get notified of new preprints

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Richard Mariadasse1 paper · Yale University;

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Organism:virus· 1

Frequent Co-Authors

Abhisek DwivedyiD· 1 shared Bichitra Kumar BiswaliD· 1 shared Chen‐Ou ZhangiD· 1 shared Deepsikha KariD· 1 shared Dhasakumar S. NavaratnamiD· 1 shared Jeyaraman JeyakanthaniD· 1 shared Jie YangiD· 1 shared Joseph Santos‐SacchiiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Abhisek DwivedyORCID

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2 papers

Recent·Most cited

Conformational changes underlying electromechanical transduction in prestin resemble a transport transition in pendrin

Chen‐Ou Zhang, Richard Mariadasse, Jie Yang, Jun-Ping Bai, Joseph Santos‐Sacchi, Dhasakumar S. Navaratnam, Oliver Beckstein

This study shows that prestin's conformational changes during electromechanical transduction resemble a transport transition in pendrin, with shared structural and functional properties.

bioRxiv · Aug 5, 2026 · PreprintBiophysics

Characterization of the NiRAN domain from RNA-dependent RNA polymerase provides insights into a potential therapeutic target against SARS-CoV-2

Abhisek Dwivedy, Richard Mariadasse, Mohammed Ahmad, Sayan Chakraborty, Deepsikha Kar, Satish Tiwari, Sankar Bhattacharyya, Sudipta Sonar, Shailendra Mani, Prafullakumar B. Tailor, Tanmay Majumdar, Jeyaraman Jeyakanthan, Bichitra Kumar Biswal

This study characterizes the NiRAN domain of SARS-CoV-2 RdRp, identifies its kinase-like activity, and predicts potential inhibitors for drug repurposing.

PLoS Computational Biology · Sep 13, 2021Peer-reviewedBioinformatics