Juan Manuel Trinidad-Barnech

The modular origin and evolutionary expansion of the enigmatic DGF-1 protein family in trypanosomatids

The paper re-annotates and characterizes the DGF-1 gene family in T. cruzi, revealing its modular structure and evolutionary history across trypanosomatids.

Origin of Eukaryotic Plasmalogen Biosynthesis by Horizontal Gene Transfer from Myxobacteria

The paper traces the origin of eukaryotic plasmalogen biosynthesis to horizontal gene transfer from Myxobacteria, revealing evolutionary divergence in plasmalogen synthesis across eukaryotic lineages.

Expanding kinetoplastid genome annotation through protein structure comparison

The paper develops a protein structure-based homology search pipeline to annotate kinetoplastid proteins, identifying 23,000 hypothetical proteins and uncovering previously undetected eukaryotic proteins.

Transcriptome-wide analysis of microRNA-mRNA correlations in unperturbed tissue transcriptomes identifies microRNA targeting determinants.

The paper analyzes microRNA-mRNA correlations in tissue transcriptomes to identify targeting determinants and provides a bioinformatic tool for predicting interactions.