Horacio Pérez‐Sánchez

The paper identifies novel mosquito repellents by repurposing drugs and food-derived compounds targeting AgamOBP4, with benzoyl peroxide showing strong repellency.

This paper identifies two fascin-binding compounds using a virtual screening approach combined with experimental validation, showing they inhibit CRC cell proliferation and migration.

The paper identifies a novel fascin inhibitor, Z1362873773, from a chemical library that inhibits cancer cell migration and shows potential as a colorectal cancer treatment.

OBE-DB predicts anti-obesity drugs using shape similarity and inverse virtual screening, offering a user-friendly tool that outperforms conventional methods in accuracy and usability.

This study identifies drug-like inhibitors that block TSG101-UEV/PTAP interactions, impairing viral budding and replication across multiple virus families.

The paper evaluates AlphaFold and molecular dynamics predictions for serpin mutations, finding they fail to capture conformational changes despite experimental evidence.

This study shows that DJ-1 metabolites GA and DL can rescue fertility and mitochondrial dysfunction in multiple species, with GA having broader effects across models.

The paper identifies cevimeline as a potential coadjuvant for obesity treatment by showing its similarity to varenicline in interacting with nicotinic α4β2-Ach receptors.