Probabilistic spike propagation shapes sympathetic output in mouse preganglionic neurons
Mallika Halder, Alan J. Sokoloff, Yaqing Li, Michael A. Sawchuk, Brittney Ward, Shawn Hochman
The paper shows that spike propagation in sympathetic preganglionic neurons is probabilistic and unreliable, particularly in slow-conducting axons, introducing a presynaptic gain-control mechanism.
bioRxiv · May 26, 2026 · PreprintNeuroscience