GenomicsbioRxivPreprint
Annotation of the non-canonical translatome reveals that CHO cell microproteins are a new class of mAb drug product impurity
Marina Castro‐Rivadeneyra, Ioanna Tzani, Paul S. Kelly…·Colin Clarke
The paper identifies microprotein impurities in mAb drug products from CHO cells using Ribo-seq and mass spectrometry, showing their abundance varies with growth phase.