Lin Zhang

This study profiles temporal RNA-seq in iPSC-derived motor neurons from ALS patients with specific mutations, identifying shared gene expression and splicing defects across different mutations.

The paper constructs a single-cell spatio-temporal atlas of molecular trajectories during gastrulation in mouse embryos, revealing asymmetric BMP signaling and its role in left-right body plan asymmetry.

The paper identifies microprotein impurities in mAb drug products from CHO cells using Ribo-seq and mass spectrometry, showing their abundance varies with growth phase.