Peng Liu

MPAC: a computational framework for inferring pathway activities from multi-omic data

MPAC infers pathway activities from multi-omic data to identify patient subgroups and clinically relevant proteins, demonstrating improved results over single-omic analyses in head and neck cancer.

Novel regulator Fpr2 controls immune homeostasis via CCL4-dependent neutrophils

This study identifies Fpr2's role in immune homeostasis by regulating neutrophil subpopulations via CCL4 and Anxa1, revealing mechanisms of bacterial resistance.

Unpaired Data Empowers Association Tests

The paper introduces SAT, a method that uses both paired and unpaired data to improve association tests between biomedical data types, showing better control of false discovery and increased power in real-world applications.