Qian Li

Dysregulation of macrophage lipid metabolism underlies intracellular bacterial neuroinvasion

This study identifies a CD36+ macrophage subpopulation that facilitates intracellular bacterial brain invasion through lipid metabolism dysregulation and glucose intervention.

Pathogen Subversion of Neuro-Epidermal Signaling Impairs Lysosomal Function to Disrupt Collagen Homeostasis

This study shows that pathogen-induced neuronal signaling disrupts lysosomal function and collagen homeostasis in C. elegans, identifying NSIF-1 and ELT-3 as key regulators.

Novel regulator Fpr2 controls immune homeostasis via CCL4-dependent neutrophils

This study identifies Fpr2's role in immune homeostasis by regulating neutrophil subpopulations via CCL4 and Anxa1, revealing mechanisms of bacterial resistance.

Single-Nuclei RNA Sequencing Identifies Type C Low-Threshold Mechanoreceptors as Key Players in Paclitaxel-Induced Peripheral Neuropathy

This study uses snRNA-seq to identify type C low-threshold mechanoreceptors as key contributors to paclitaxel-induced neuropathic pain.