Jack L. Browning

This study shows that astrocyte TrkB.T1 is essential for synapse formation and astrocyte-synapse interactions, with loss of TrkB.T1 reducing synapse density and interactions.

This study shows that Aβ deposition in meningeal arteries correlates with reduced cerebral blood flow and collateral vessel remodeling in a mouse model of AD, with sex differences in Aβ burden.

This study identifies increased chondroitin sulfate proteoglycans (CSPGs) in the hippocampus and amygdala as a cause of infection-induced epilepsy, showing their role in neuronal hyperexcitability and potential as a therapeutic target.