A novel functional gene delivery platform based on a commensal human anellovirus demonstrates transduction in multiple tissue types
Cato Prince, George S. Bounoutas, Bolu Zhou, Waseem Khan Raja, Isabella Gold, Riana Pozsgai, Parmi Thakker, Nicole M. Boisvert, Christopher Reardon, Stephanie Thurmond, Erin Ozturk, Rajendra Boggavarapu, Jenna M. Antonucci, Patricio Jeraldo, Simeon U. Springer, , Joseph M. Cabral
This paper develops a gene delivery vector based on a human anellovirus, demonstrating transduction in multiple tissues and durable in vivo function in mice.
Molecular Therapy — Methods & Clinical Development · Sep 23, 2025Peer-reviewedBioengineering