BioinformaticsbioRxivPreprint
Single-nucleus co-expression networks of dopaminergic neurons support iron accumulation as a plausible explanation to their vulnerability in Parkinson's disease
Alicia Gómez-Pascual, Araks Martirosyan, Katja Hebestreit…·Juan Antonio Botía
The paper introduces scCoExpNets and CovCoExpNets to analyze cell-type specific gene co-expression networks from single-cell RNA-seq data, identifying iron accumulation as a factor in dopaminergic neuron vulnerability in Parkinson's disease.