Yihang Zhou

Unified modeling of mutation-induced protein stability responses with OmegaTherm

OmegaTherm predicts mutation-induced protein stability responses by jointly modeling folding free energy and melting temperature, achieving state-of-the-art performance in prediction and variant ranking.

ProteinConformers: large-scale and energetically profiled descriptions of protein conformational landscapes

ProteinConformers provides a large-scale dataset of protein conformations with energy profiles and similarity annotations, offering a benchmarking framework and analysis platform.