Synthetic BiologybioRxivPreprint
Automated, self-resistance gene-guided, and high-throughput genome mining of bioactive natural products from Streptomyces
Yujie Yuan, Chunshuai Huang, Nilmani Singh…·Huimin Zhao
The paper introduces a high-throughput platform for discovering bioactive natural products from Streptomyces by combining computational prediction, cloning, and heterologous expression of biosynthetic gene clusters.