NeuroscienceMolecular TherapyPeer-reviewed
Functional repair after ischemic injury through high efficiency in situ astrocyte-to-neuron conversion
Yu‐Chen Chen, Ningxin Ma, Zi-Fei Pei…·Gong Chen
This study demonstrates high-efficiency in situ astrocyte-to-neuron conversion in adult mammalian brains to repair ischemic injury, generating sufficient new neurons to cover 40% of lost neurons and improve motor and memory function.
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