Angelica M. Minier-Toribio

The paper identifies synaptic bioenergetic remodeling in the mPFC after heroin abstinence, but not cocaine, and links it to relapse vulnerability.

This study identifies a dysfunctional nucleus accumbens ensemble in Shank3-/- mice that drives social avoidance by hyperresponding to social novelty.

The paper identifies a shared transcriptional network in the nucleus accumbens that supports stress resilience in both sexes and shows causal effects of hub genes.

The paper identifies a role for prefrontal cortex astrocytes in stress resilience using mouse models and RNA-sequencing, showing distinct transcriptional responses between resilient and susceptible mice.

This study identifies an anterior cingulate cortex neuronal ensemble that mediates context-based opioid analgesic tolerance without affecting basal nociception.

The paper investigates cocaine-induced astrocyte-specific transcriptome in mice, identifies CREB as a key regulator, and shows its role in modulating neuronal and behavioral responses to cocaine.

This study identifies D1 and D2 dopamine receptor-expressing neurons in the mouse ventral hippocampus and shows they mediate opposing approach/avoidance behaviors during anxiety-related tasks.

This study examines neural activity in the basolateral and central amygdala during reward seeking under punishment, finding that opposing neuronal populations in the CeA control reward-seeking behavior despite adverse consequences.

This study shows that E2F3a overexpression in D1-MSNs increases cocaine reward in both male and female mice, while knockdown has opposite effects, with no impact in D2-MSNs.

This study identifies H3K27me1 as a chromatin scar that mediates lifelong stress susceptibility through its role in altering gene expression in the nucleus accumbens.

The paper compares gene expression in the nucleus accumbens during cocaine withdrawal and extinction in rats, identifying distinct transcriptional patterns associated with different behavioral outcomes.

This study shows that astrocytic CREB in the nucleus accumbens influences susceptibility to chronic stress through transcriptional changes.

This study identifies transcriptional changes in the brain reward circuit across heroin exposure and seeking behaviors in mice, revealing molecular mechanisms and potential therapeutic targets for opioid use disorder.

This study shows that ventral subiculum neuronal ensembles are specifically involved in the incubation of oxycodone craving after voluntary abstinence, but not after forced abstinence or early abstinence.

The paper investigates how CREB function in specific brain regions influences distinct forms of regret related to resilience and susceptibility to chronic stress in mice.

This study maps ΔFOSB binding sites in nucleus accumbens neurons after chronic cocaine exposure using CUT&RUN, revealing enhancer-like regions and interactions with BRG1 and other transcription factors.

This study demonstrates high-efficiency in situ astrocyte-to-neuron conversion in adult mammalian brains to repair ischemic injury, generating sufficient new neurons to cover 40% of lost neurons and improve motor and memory function.

The paper shows that olfactory bulb activity coordinates with entorhinal circuits in neonatal mice through theta bursts and odor exposure.