The germline coordinates mitokine signaling
Koning Shen, Jenni Durieux, Cesar Mena, Brant Michael Webster, C. Kimberly Tsui, Hanlin Zhang, Larry K. Joe, Kristen M. Berendzen, Andrew G. Dillin
The paper shows that germline mitochondria mediate neuron-to-peripheral UPRMT signaling in C. elegans by responding to mitokines like WNT and serotonin and regulating lipid metabolic pathways.
Cell · Jul 2, 2024Peer-reviewedGenetics