Nikoletta Psatha

This study demonstrates in vivo gene therapy for hemoglobinopathies using EPOR editing to enhance the expansion of gene-corrected erythroid cells without drug selection.

The paper identifies potent, compact, and lineage-specific enhancers for gene therapy vectors using epigenomic data and validates their efficacy in correcting a thalassemia phenotype.

The paper maps enhancer gene regulatory networks (GRNs) in liver cell types and identifies TFs governing hepatocyte zonation states using multiomics and deep learning.

This study maps chromatin dynamics and gene expression during human erythropoiesis, revealing regulatory modules that guide lineage commitment and maturation.