Author

Mineo Iwata

Altius Institute for Biomedical Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Grigorios GeorgolopoulosiD· 2 shared Jeff D. VierstraiD· 2 shared John A. StamatoyannopoulosiD· 2 shared Nikoletta PsathaiD· 2 shared Alexandra KirtsouiD· 1 shared Andrew NishidaiD· 1 shared Evangelia YannakiiD· 1 shared George Stamatoyannopoulos· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersGenomics

Grigorios GeorgolopoulosORCID

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2 papers

Recent·Most cited

Large-scale discovery of potent, compact and lineage specific enhancers for gene therapy vectors

Nikoletta Psatha, Pavel Sova, Grigorios Georgolopoulos, Kiriaki Paschoudi, Mineo Iwata, Jordan E. Bloom, Tatyana Ulyanova, Hao Wang, Alexandra Kirtsou, Ninos-Ioannis Vasiloudis, Matthew S. Wilken, John A. Stamatoyannopoulos, Evangelia Yannaki, Thalia Papayannopoulou, George Stamatoyannopoulos, Jeff D. Vierstra

The paper identifies potent, compact, and lineage-specific enhancers for gene therapy vectors using epigenomic data and validates their efficacy in correcting a thalassemia phenotype.

bioRxiv · Oct 4, 2023 · PreprintGenomics

Chromatin dynamics during hematopoiesis reveal discrete regulatory modules instructing differentiation

Grigorios Georgolopoulos, Nikoletta Psatha, Mineo Iwata, Andrew Nishida, Tannishtha Som, Minas Yiangou, John A. Stamatoyannopoulos, Jeff D. Vierstra

This study maps chromatin dynamics and gene expression during human erythropoiesis, revealing regulatory modules that guide lineage commitment and maturation.

bioRxiv · Apr 2, 2020 · PreprintDevelopmental Biology