Author

John A. Hanover

National Institutes of HealthORCID 0000-0002-3154-9878Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Cell Biology· 1

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Organism:C. elegans· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Daniel KonzmaniD· 2 shared Andy GoldeniD· 1 shared Antonio ArtiguesiD· 1 shared Aspin R. Denson· 1 shared Chad M SlawsoniD· 1 shared Dakota R. RobartsiD· 1 shared Ee Phie TaniD· 1 shared Halyna Fedosyuk· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenetics

Daniel KonzmanORCID

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Author profile →

3 papers

Recent·Most cited

Multi-Omics after O-GlcNAc Alteration Identifies Cellular Processes Working Synergistically to Promote Aneuploidy

Samuel S. Boyd, Dakota R. Robarts, Khue Nguyen, Maite T. Villar, Ibtihal M. Alghusen, Manasi Kotulkar, Aspin R. Denson, Halyna Fedosyuk, Stephen A. Whelan, Norman C.Y. Lee, John A. Hanover, Wagner B. Dias, Ee Phie Tan, Steven R. McGreal, Antonio Artigues, , Chad M Slawson

The paper uses multi-omics analysis to show OGT regulates aneuploidy by fine-tuning multiple cellular pathways through O-GlcNAcylation.

Molecular Metabolism · Oct 30, 2024Peer-reviewedCell Biology

O-GlcNAc transferase plays a non-catalytic role in C. elegans male fertility

Daniel Konzman, Tetsunari Fukushige, Mesgana Dagnachew, Michael Krause, John A. Hanover

This study shows that O-GlcNAc transferase (OGT) has a non-catalytic role in male fertility in C. elegans by affecting mating behavior, not through its enzymatic activity.

PLoS Genetics · Nov 16, 2022Peer-reviewedGenetics

Nutrient sensing pathways regulating adult reproductive diapause in C. elegans

Moriah Eustice, Daniel Konzman, Jeff M. Reece, Salil K Ghosh, Jhullian J. Alston, Tyler J. Hansen, Andy Golden, Michelle R. Bond, Lara K. Abramowitz, John A. Hanover

The paper identifies genetic pathways regulating adult reproductive diapause in C. elegans through a candidate-based genetic screen, revealing roles for fatty acid metabolism, sirtuins, and the O-GlcNAc pathway in initiation and TOR in recovery.

PLoS ONE · Sep 16, 2022Peer-reviewedGenetics