Author

Ee Phie Tan

Scripps Research InstituteORCID 0000-0003-1352-0366Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ee Phie Tan1 paper

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1

Frequent Co-Authors

Christian M. ColeiD· 2 shared Evan T. PowersiD· 2 shared Jeffery W. KellyiD· 2 shared Alex Matthewson· 1 shared Anne-Laure Mahul-Mellier· 1 shared Beatrice CostaiD· 1 shared Bianca Barth· 1 shared Carl Ash· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Christian M. ColeORCID

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2 papers

Recent·Most cited

Autophagy activator AA-20 engages CDK5 to promote lipophagy and improve neurodegeneration-associated phenotypes

Ee Phie Tan, Lydia Ambaye, Anne-Laure Mahul-Mellier, Yuting Zhang, Patricia Martinez-Botia, Sergio R. Labra, Lynee A. Massey, Zi Gao, Zainab Ahmed, Karina Nugroho, Carl Ash, Wen Ren, Christian M. Cole, Yin Wu, Sarah Ly, , Jeffery W. Kelly

AA-20 promotes lipophagy by activating lysosomal acid lipase and CDK5, reducing lipid droplet accumulation and improving neurodegeneration-associated phenotypes in cellular and organoid models.

bioRxiv · Nov 2, 2026 · PreprintMolecular Biology

A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway

Overall coordination, Suzanne Elsasser, Lisa P. Elia, Richard I. Morimoto, Evan T. Powers, Daniel J. Finley, Beatrice Costa, Maher Budron, Zachary Tokuno, Shijie Wang, Rajshri G. Iyer, Bianca Barth, Eric Mockler, Steven M. Finkbeiner, Jason E. Gestwicki, , Ralph A. Nixon

The paper curates a list of 838 high-confidence components of the autophagy-lysosome pathway as part of a comprehensive effort to define the human proteostasis network.

bioRxiv · Mar 22, 2023 · PreprintBioinformatics