Author

Christopher A. Desjardins

Broad InstituteORCID 0000-0002-3160-4734Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:fungi (other)· 2 Research Focus:GWAS / association mapping· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Christina A. CuomoiD· 3 shared Anastasia P. LitvintsevaiD· 2 shared John R. PerfectiD· 2 shared Joseph HeitmaniD· 2 shared Sean M. Sykes· 2 shared Yuan CheniD· 2 shared Abigail L. MansoniD· 1 shared Alexander M. Jones· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersGenomics

Christina A. CuomoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedNov 2, 2024

Distinct Escherichia coli transcriptional profiles in the guts of recurrent UTI sufferers revealed by pangenome hybrid selection

M. G. Young, Timothy J. Straub, Colin J. Worby…·Ashlee M. Earl

This study identifies distinct E. coli transcriptional profiles in the guts of recurrent UTI sufferers using a novel pangenome hybrid selection method.

13 citations

E. colibulk RNA-seq

GeneticsPLoS PathogensPeer-reviewedJan 14, 2019

Antagonistic paralogs control a switch between growth and pathogen resistance in C. elegans

Kirthi C. Reddy, Tal Dror, Ryan S. Underwood…·Emily R. Troemel

This study identifies two C. elegans-specific genes, pals-22 and pals-25, which function as antagonistic regulators controlling the switch between growth and pathogen resistance.

100 citationstop 4%

C. elegansexperimental assay

GenomicsGeneticsPeer-reviewedJul 5, 2017

Population Genomics Of Cryptococcus neoformans var. grubii Reveals New Biogeographic Relationships And Finely Maps Hybridization

Johanna L. Rhodes, Christopher A. Desjardins, Sean M. Sykes…·Christina A. Cuomo

This study analyzes the population genomics of Cryptococcus neoformans var. grubii, revealing hybridization, biogeographic relationships, and genetic structure across global isolates.

96 citationstop 2%

fungi (other)whole-genome sequencing

GenomicsGenome ResearchPeer-reviewedJul 1, 2017

Population Genomics And The Evolution Of Virulence In The Fungal Pathogen Cryptococcus neoformans

Christopher A. Desjardins, Charles D. Giamberardino, Sean M. Sykes…·Christina A. Cuomo

This study uses population genomics to explore how environmental selective pressures shaped virulence traits in Cryptococcus neoformans, identifying genetic differences between clinical and environmental isolates.

157 citations

fungi (other)whole-genome sequencing