Multivalent assembly of PAR-3/aPKC complexes establishes cell polarity in C. elegans zygotes
Sheng-Ping Hsu, Daniel J. Dickinson
This study shows how PAR-3/aPKC cooperativity establishes cell polarity in C. elegans zygotes through multivalent assembly, with PLK-1 regulating its downregulation during polarity maintenance.
bioRxiv · Apr 16, 2025 · PreprintCell Biology