Author

George D. Bachand

Sandia National LaboratoriesORCID 0000-0002-3169-9980Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Emily M. LaytoniD· 1 shared Eric M. SmalliD· 1 shared Gina M. GeiselmaniD· 1 shared Jesse L. CahilliD· 1 shared Laura D. Weinstock· 1 shared Michael Bernauer· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Emily M. LaytonORCID

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1 paper

Recent·Most cited

The phage stress test: a proving ground for genome language models in biological prediction

Emily M. Layton, Michael Bernauer, Laura D. Weinstock, Eric M. Small, Gina M. Geiselman, George D. Bachand, Jesse L. Cahill

This study evaluates a genome language model's ability to predict the effects of sequence changes in phages using experimental data, finding mixed success in distinguishing functional from nonfunctional mutations.

bioRxiv · Sep 24, 2026 · PreprintBioinformatics