Emily M. Layton

The paper reconstructs the MS2 phage genome using cDNA and shows that the current NCBI reference genome does not produce infectious phage, highlighting the need to verify reference genome infectivity.

This study evaluates a genome language model's ability to predict the effects of sequence changes in phages using experimental data, finding mixed success in distinguishing functional from nonfunctional mutations.

The paper identifies cifA as the gene responsible for rescuing cytoplasmic incompatibility in Drosophila melanogaster, establishing a Two-by-One model for CI genetics.