Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion
Jaewook Hwang, Jonathan Kirshner, Daniel André Ramey Deschênes…·Yang Qu
This study identifies and characterizes a conserved oxidase-reductase pair responsible for C3 stereochemistry inversion in monoterpenoid indole alkaloids and traces the evolutionary origin of the gene clusters involved.