Author

Jaewook Hwang

University of New Brunswick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:plant (other)· 2 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Jacob Owen PerleyiD· 2 shared Jiazhang LianiD· 2 shared Jorge Jonathan Oswaldo Garza‐GarcíaiD· 2 shared Matthew Bailey RichardsoniD· 2 shared Mohammadamin ShahsavaraniiD· 2 shared Yang QuiD· 2 shared Alyssa Dawn Seveck· 1 shared Barry A. BlightiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersSynthetic Biology

Jacob Owen PerleyORCID

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2 papers

Recent·Most cited

A cinnamyl alcohol dehydrogenase-like scaffold organizes monoterpenoid indole alkaloid biosynthesis

Di Gao, Scott Galeung Alexander Mann, Binbin Chen, Yuanwei Gou, Cong Chen, Chong Qiao, Jorge Jonathan Oswaldo Garza‐García, Mohammadamin Shahsavarani, Xiaojing Jiang, Hannah Caroline Tran, Jingfei Bao, Mathew Bailey Richardson, Li J, Jacob Owen Perley, Jaewook Hwang, , Jiazhang Lian

The paper identifies VinBLAST, a scaffold protein that facilitates the biosynthesis of monoterpenoid indole alkaloids by enhancing the interaction and activity of key enzymes.

Science · Jul 16, 2026Peer-reviewedSynthetic Biology

Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion

Jaewook Hwang, Jonathan Kirshner, Daniel André Ramey Deschênes, Matthew Bailey Richardson, Steven J. Fleck, Scott Galeung Alexander Mann, Jun Guo, Jacob Owen Perley, Mohammadamin Shahsavarani, Jorge Jonathan Oswaldo Garza‐García, Alyssa Dawn Seveck, Savannah Sadie Doiron, Zhan Mai, Stephen Nelson Silliphant, Sarah A. Englehart, , Yang Qu

This study identifies and characterizes a conserved oxidase-reductase pair responsible for C3 stereochemistry inversion in monoterpenoid indole alkaloids and traces the evolutionary origin of the gene clusters involved.

Nature Communications · Nov 25, 2025Peer-reviewedBiochemistry