Jorge Jonathan Oswaldo Garza‐García

The paper identifies VinBLAST, a scaffold protein that facilitates the biosynthesis of monoterpenoid indole alkaloids by enhancing the interaction and activity of key enzymes.

This study identifies and characterizes a conserved oxidase-reductase pair responsible for C3 stereochemistry inversion in monoterpenoid indole alkaloids and traces the evolutionary origin of the gene clusters involved.

This study investigates the stereochemical outcomes of enzymes involved in sarpagan and akuammiline alkaloid biosynthesis, revealing how enzymatic activities control C16 stereochemistry across species.

This study identifies and characterizes three new CYPs in T. litoralis that catalyze specific oxidations of four MIA skeletons, expanding understanding of MIA biosynthesis.

This study improves yeast-based biosynthesis of monoterpenoid indole alkaloids by expressing a key enzyme and integrating biosynthetic gene cassettes, enabling production of vinblastine precursors and their unnatural derivatives.