Author

Jennifer A. Kelly

Oklahoma Medical Research FoundationORCID 0000-0002-3203-2467Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:DNA methylation· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Patrick M. GaffneyiD· 3 shared Kandice L. TessneeriD· 2 shared Albin BjörkiD· 1 shared Amy Darise FarrisiD· 1 shared Anna M. StolarczykiD· 1 shared Astrid RasmusseniD· 1 shared Audrey A. Johnston· 1 shared Betty P. TsaoiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Patrick M. GaffneyORCID

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3 papers

Recent·Most cited

Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

Mandi M. Wiley, Marcin Radziszewski, Bhuwan Khatri, Michelle L. Joachims, Kandice L. Tessneer, Anna M. Stolarczyk, Songyuan Yao, James Li, C. Pritchett Frazee, Audrey A. Johnston, Astrid Rasmussen, Juan‐Manuel Anaya, Lara A. Aqrawi, Sang‐Cheol Bae, Eva Baecklund, , Christopher J. Lessard

The paper identifies five SNPs in the DDX6-CXCR5 locus associated with autoimmune diseases and shows their functional effects on gene regulation in immune and epithelial cells.

Annals of the Rheumatic Diseases · May 29, 2025Peer-reviewedGenetics

Massively Parallel Reporter Assay Confirms Regulatory Potential of hQTLs and Reveals Important Variants in Lupus and Other Autoimmune Diseases

Yao Fu, Jennifer A. Kelly, Jaanam Gopalakrishnan, Richard C. Pelikan, Kandice L. Tessneer, Satish Pasula, Kiely M. Grundahl, David A. Murphy, Patrick M. Gaffney

The paper uses a massively parallel reporter assay to identify variants influencing gene expression in lupus and autoimmune diseases, finding hQTLs are more functional than eQTLs and identifying 31 putative causal variants.

Human Genetics and Genomics Advances · Feb 23, 2024Peer-reviewedGenomics

Comparison of the three-dimensional chromatin structures of adolescent and adult peripheral blood B cells: implications for the study of pediatric autoimmune diseases

Kaiyu Jiang, Yao Shi Fu, Jennifer A. Kelly, Patrick M. Gaffney, Lucy Holmes, James N. Jarvis

This study compares 3D chromatin structures of pediatric and adult B cells, finding similar architectures across age groups and suggesting adult datasets may suffice for studying pediatric autoimmune diseases.

bioRxiv · Sep 11, 2023 · PreprintGenomics