Yao Fu

The paper uses a massively parallel reporter assay to identify variants influencing gene expression in lupus and autoimmune diseases, finding hQTLs are more functional than eQTLs and identifying 31 putative causal variants.

The paper identifies gene targets at risk loci for skin-related disorders by integrating HiChIP data from relevant cell lines and public datasets.

This paper introduces ecTMB, a statistical framework for estimating and classifying tumor mutational burden, identifying a new TMB subtype associated with patient survival.

This study uses Capture Hi-C and CRISPR activation to identify KLF4 as a target gene in the 9q31 psoriasis risk locus, linking GWAS variants to functional interactions.

ALoFT annotates and predicts the disease-causing potential of loss-of-function variants across different genetic contexts and populations.