ImmunologybioRxivPreprint
Neoadjuvant anti-4-1BB confers protection against spontaneous metastasis through low-affinity intratumor CD8+ T cells in triple-negative breast cancer
Bryan Jian Wei Lim, Mingyong Liu, Liuyang Wang…·Qi-Jing Li
This study shows that neoadjuvant anti-4-1BB therapy reduces metastasis by enhancing Tint cell clonal expansion and T cell egress in TNBC.
DOI 10.1101/2025.01.29.635356