Qi-Jing Li

This study shows that amyloid-β precursor protein (APP) promotes tumor growth by creating an immune-exclusive tumor microenvironment through suppression of CD8+ T cell and NK cell immunity.

This study shows that neoadjuvant anti-4-1BB therapy reduces metastasis by enhancing Tint cell clonal expansion and T cell egress in TNBC.

B-Lightning identifies marker genes and cell subpopulations for specific sources of heterogeneity while filtering out confounding factors, improving sensitivity and robustness in single-cell data analysis.

This study uses scRNA-seq to analyze the tumor microenvironment and cell types in ovarian clear cell carcinoma, identifying immune infiltration and similarities with endometriosis.

SifiNet identifies gene sets and annotates cells without clustering, showing better performance than existing methods on multiomic data.

This paper introduces CDI, a new unsupervised measure to evaluate scRNA-seq clustering accuracy and select optimal parameters.