GenomicsGenome biologyPeer-reviewed
DNA Topoisomerase I differentially modulates R-loops across the human genome
Stefano Giustino Manzo, Stella R. Hartono, Lionel A. Sanz…·Frederic L. Chedin
This study shows DNA Topoisomerase I regulates R-loop formation by causing gains and losses at different genomic regions, affecting replication and cell cycle progression.
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