R.P. Vivek-Ananth

Curcumin and Sulforaphane Preserve Mobility in Aging Caenorhabditis elegans via Distinct yet Complementary Transcriptional Signatures

This study shows curcumin and sulforaphane improve mobility in aging C. elegans through distinct transcriptional mechanisms, with their combination enhancing detoxification and reducing immune gene expression.

sCentInDB: A database of essential oil chemical profiles of Indian medicinal plants

sCentInDB is a manually curated database of essential oil chemical profiles from 554 Indian medicinal plants, providing metadata and chemical space analysis for research and quality standards.

T9GPred: A Comprehensive Computational Tool for the Prediction of Type 9 Secretion System, Gliding Motility and the Associated Secreted Proteins

T9GPred predicts Type 9 secretion system, gliding motility, and associated secreted proteins in Bacteroidetes strains using curated experimental data and signal domain analysis.

MeFSAT: A curated natural product database specific to secondary metabolites of medicinal fungi

MeFSAT is a curated database of secondary metabolites from medicinal fungi, providing chemical and therapeutic information to aid drug discovery.

A curated knowledgebase enabling a network perspective on endocrine disrupting chemicals and their biological systems-level perturbations

The paper compiles and curates a database of endocrine disrupting chemicals (EDCs) with their toxicity profiles and builds networks to analyze their chemical and biological relationships.

Comparative systems analysis of the secretome of the opportunistic pathogen Aspergillus fumigatus and other Aspergillus species

The paper identifies secreted and cell membrane proteins in ten Aspergillus species and finds their secretomes are more antigenic and structurally similar to known drug targets.

IMPPAT: A curated database of Indian Medicinal Plants, Phytochemistry And Therapeutics

IMPPAT is a curated database of Indian medicinal plants, phytochemistry, and therapeutics, providing a resource for natural product-based drug discovery with 9596 phytochemicals and 1124 therapeutic uses.

Advances in the integration of transcriptional regulatory information into genome-scale metabolic models

This paper reviews methods for integrating transcriptional regulatory data into genome-scale metabolic models to enhance their predictive capabilities.