David Weinkove

This paper uses pesticide toxicity data to identify substances that improve survival and healthspan by affecting mitochondrial bioenergetics.

This study shows curcumin and sulforaphane improve mobility in aging C. elegans through distinct transcriptional mechanisms, with their combination enhancing detoxification and reducing immune gene expression.

This paper develops tools to study Pseudomonas aeruginosa infection and biofilm formation in vivo using C. elegans, identifying RhlR as a potential antimicrobial target.

This study identifies SKN-1B in C. elegans as a central food-responsive node that controls satiety and metabolic homeostasis by modulating endocrine pathways and mitochondrial networks.